2024

Expression of HIF1α in intestinal epithelium restricts arthritis inflammation by inhibiting RIPK3-induced cell death machinery

Pang Lyu, Jinming Wen, Wenshuo Zhang, Ning Liu, Iris Stolzer, Andreas Gießl, Yewei Jia, Daniele Mauro, Fulin Zhang, Francesco Ciccia, Didier Soulat, Claudia Günther, Georg Schett, Aline Bozec

Eosinophils preserve bone homeostasis by inhibiting excessive osteoclast formation and activity via eosinophil peroxidase

Darja Andreev, Katerina Kachler, Mengdan Liu, Zhu Chen, Brenda Krishnacoumar, Mark Ringer, Silke Frey, Gerhard Krönke, David Voehringer, Georg Schett, Aline Bozec

2023:

Impact of Microbiome-Brain Communication on Neuroinflammation and Neurodegeneration

Iris Stolzer, Eveline Scherer, Patrick Süß, Veit Rothhammer, Beate Winner, Markus F Neurath, Claudia Günther

L-arginine metabolism inhibits arthritis and inflammatory bone loss

Shan Cao, Yixuan Li, Rui Song, Xianyi Meng, Maximilian Fuchs, Chunguang Liang, Katerina Kachler, Xinyu Meng, Jinming Wen, Ursula Schlötzer-Schrehardt, Verena Taudte, Arne Gessner, Meik Kunz, Ulrike Schleicher, Mario M Zaiss, Alf Kastbom, Xiaoxiang Chen, Georg Schett, Aline Bozec

High-fat-diet-associated intestinal microbiota exacerbates psoriasis-like inflammation by enhancing systemic γδ T cell IL-17 production

Koshiro Sonomoto, Rui Song, Daniel Eriksson, Anne M Hahn, Xianyi Meng, Pang Lyu, Shan Cao, Ning Liu, R Verena Taudte, Stefan Wirtz , Yoshiya Tanaka, Thomas H Winkler, Georg Schett, Didier Soulat, Aline Bozec

2022:

Inflammatory activation of the FcγR and IFNγR pathways co-influences the differentiation and activity of osteoclasts

Bettina Groetsch, Elisabeth Schachtschabel, Philipp Tripal, Benjamin Schmid, Ana-Suncana Smith, Georg Schett, Aline Bozec

Epithelial HIF2α expression induces intestinal barrier dysfunction and exacerbation of arthritis

Jinming Wen, Pang Lyu, Iris Stolzer, Jin Xu, Andreas Gießl, Zhen Lin, Darja Andreev, Katerina Kachler, Rui Song, Xianyi Meng, Shan Cao, Giuliana Guggino, Francesco Ciccia, Claudia Günther, Georg Schett, Aline Bozec

2021:

The Transcription Factor FRA-1/AP-1 Controls Lipocalin-2 Expression and Inflammation in Sepsis Mode

Shan Cao, Anne Schnelzer, Nicole Hannemann, Georg Schett, Didier Soulat, Aline Bozec

Systemic PPARγ Antagonism Reduces Metastatic Tumor Progression in Adipocyte-Rich Bone in Excess Weight Male Rodents

Anastasia Gaculenko, Gasper Gregoric, Vanessa Popp, Lisa Seyler, Mark Ringer, Katerina Kachler, Zhengquan Wu, Wadim Kisel, Christine Hofbauer, Lorenz C Hofbauer, Michael Uder, Georg Schett, Tobias Bäuerle, Aline Bozec

2020:  Regulatory eosinophils induce the resolution of experimental arthritis and appear in remission state of human rheumatoid arthritis

Darja Andreev, Mengdan Liu, Katerina Kachler, Mireia Llerins Perez, Philipp Kirchner, Julia Kölle, Andreas Gießl, Simon Rauber, Rui Song, Oliver Aust, Anika Grüneboom, Arnd Kleyer, Juan D Cañete, Arif Ekici, Andreas Ramming, Susetta Finotto, Georg Schett, Aline Bozec

Environmental Microbial Factors Determine the Pattern of Inflammatory Lesions in a Murine Model of Crohn’s Disease-Like Inflammation

Iris Stolzer, Valentina Kaden-Volynets, Barbara Ruder, Marilena Letizia, Miriam Bittel, Philipp Rausch, Marijana Basic, André Bleich, John F Baines, Markus F Neurath, Stefan Wirtz, Carl Weidinger, Stephan C Bischoff, Christoph Becker, Claudia Günther

2019:  Interferon Lambda Promotes Paneth Cell Death Via STAT1 Signaling in Mice and Is Increased in Inflamed Ileal Tissues of Patients With Crohn’s Disease.

Günther C, Ruder B, Stolzer I, Dorner H, He GW, Chiriac MT, Aden K, Strigli A, Bittel M, Zeissig S, Rosenstiel P, Atreya R, Neurath MF, Wirtz S, Becker C.

How Autoantibodies Regulate Osteoclast Induced Bone Loss in Rheumatoid Arthritis

Ulrike Steffen, Georg Schett, and Aline Bozec