Projekt B1

Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids

Jean-Philippe Auger, Max Zimmermann, Maria Faas, Ulrich Stifel, David Chambers, Brenda Krishnacoumar, R Verena Taudte, Charlotte Grund, Gitta Erdmann, Carina Scholtysek, Stefan Uderhardt, Oumaima Ben Brahim, Mónica Pascual Maté, Cornelia Stoll, Martin Böttcher, Katrin Palumbo-Zerr, Matthew S J Mangan, Maria Dzamukova, Markus Kieler, Melanie Hofmann, Stephan Blüml, Gernot Schabbauer, Dimitrios Mougiakakos, Uwe Sonnewald, Fabian Hartmann, David Simon, Arnd Kleyer, Anika Grüneboom, Susetta Finotto, Eicke Latz, Jörg Hofmann, Georg Schett, Jan Tuckermann, Gerhard Krönke

2023:

Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes

Stephan Culemann, Katharina Knab, Maximilien Euler, Anja Wegner, Hilal Garibagaoglu, Jochen Ackermann, Kim Fischer, Deborah Kienhöfer, Georgiana Crainiciuc, Jonas Hahn, Anika Grüneboom, Falk Nimmerjahn, Stefan Uderhardt, Andrés Hidalgo, Georg Schett, Markus H Hoffmann, Gerhard Krönke

2022:

Anti-CD19 CAR T cell therapy for refractory systemic lupus erythematosus

Andreas Mackensen, Fabian Müller, Dimitrios Mougiakakos, Sebastian Böltz, Artur Wilhelm, Michael Aigner, Simon Völkl, David Simon, Arnd Kleyer, Luis Munoz, Sascha Kretschmann, Soraya Kharboutli, Regina Gary, Hannah Reimann, Wolf Rösler, Stefan Uderhardt, Holger Bang, Martin Herrmann, Arif Bülent Ekici, Christian Buettner, Katharina Maria Habenicht, Thomas H Winkler, Gerhard Krönke, Georg Schett

Comparison of physician and artificial intelligence-based symptom checker diagnostic accuracy

Markus Gräf, Johannes Knitza, Jan Leipe, Martin Krusche, Martin Welcker, Sebastian Kuhn, Johanna Mucke, Axel J Hueber, Johannes Hornig, Philipp Klemm, Stefan Kleinert, Peer Aries, Nicolas Vuillerme, David Simon, Arnd Kleyer, Georg Schett, Johanna Callhoff

Remote self-collection of capillary blood using upper arm devices for autoantibody analysis in patients with immune-mediated inflammatory rheumatic diseases

Joshua Zarbl, Ekaterina Eimer, Camilla Gigg, Gerlinde Bendzuck, Marianne Korinth, Corinna Elling-Audersch, Arnd Kleyer, David Simon, Sebastian Boeltz, Martin Krusche, Johanna Mucke, Felix Muehlensiepen, Nicolas Vuillerme, Gerhard Krönke, Georg Schett, Johannes Knitza

Accuracy and tolerability of self-sampling of capillary blood for analysis of inflammation and autoantibodies in rheumatoid arthritis patients-results from a randomized controlled trial

Johannes Knitza, Koray Tascilar, Nicolas Vuillerme, Ekaterina Eimer, Paul Matusewicz, Giulia Corte, Louis Schuster, Timothée Aubourg, Gerlinde Bendzuck, Marianne Korinth, Corinna Elling-Audersch , Arnd Kleyer, Sebastian Boeltz, Axel J Hueber, Gerhard Krönke, Georg Schett, David Simon

TELERA—Asynchronous TELEmedicine for Patients With Rheumatoid Arthritis: Study Protocol for a Prospective, Multi-Center, Randomized Controlled Trial

Johanna Mucke, Johannes Knitza, Felix Muehlensiepen, Manuel Grahammer, Ramona Stenzel, David Simon, Arnd Kleyer, Gerhard Krönke, Charlotte Sharp, Gerlinde Bendzuck, Marianne Korinth, Corinna Elling-Audersch, Nicolas Vuillerme, Georg Schett, Ann-Christin Pecherand, Martin Krusche

2021:

IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation

Maria Faas, Natacha Ipseiz, Jochen Ackermann, Stephan Culemann, Anika Grüneboom, Fenja Schröder, Tobias Rothe, Carina Scholtysek, Martin Eberhardt, Martin Böttcher, Philipp Kirchner, Cornelia Stoll, Arif Ekici, Maximilian Fuchs, Meik Kunz, Benno Weigmann, Stefan Wirtz, Roland Lang, Joerg Hofmann, Julio Vera, David Voehringer, Alessandro Michelucci, Dimitrios Mougiakakos, Stefan Uderhardt, Georg Schett, Gerhard Krönke

CD19-Targeted CAR T Cells in Refractory Systemic Lupus Erythematosus

Dimitrios Mougiakakos, Gerhard Krönke, Simon Völkl, Sascha Kretschmann, Michael Aigner, Soraya Kharboutli, Sebastian Böltz, Bernhard Manger, Andreas Mackensen, Georg Schett

2019: Origin and function of synovial macrophage subsets during inflammatory joint disease

Stephan Culemann, Anika Grüneboom, Gerhard Krönke

Locally renewing resident synovial macrophages provide a protective barrier for the joint.

Culemann S, Grüneboom A, Nicolás-Ávila JÁ, Weidner D, Lämmle KF, Rothe T, Quintana JA, Kirchner P, Krljanac B, Eberhardt M, Ferrazzi F, Kretzschmar E, Schicht M, Fischer K, Gelse K, Faas M, Pfeifle R, Ackermann JA, Pachowsky M, Renner N, Simon D, Haseloff RF, Ekici AB, Bäuerle T, Blasig IE, Vera J, Voehringer D, Kleyer A, Paulsen F, Schett G, Hidalgo A, Krönke G